Thursday, October 13, 2011

The Nobel Prize Winner in Physiology or Medicine 2011: Bruce A. Beutler, Jules A. Hoffmann & Ralph M. Steinman

The Nobel Assembly has announced to award the Nobel Prize in Physiology or Medicine 2011 with one half jointly to Bruce A. Beutler at the Scripps Research Institute in California and Jules A. Hoffmann at the French National Center for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman at the Rockefeller University in New York City for his discovery of the dendritic cell and its role in adaptive immunity on October 3, 2011 at Karolinska Institute.
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The Nobel Prize Winners in Physiology or Medicine 2011


Bruce A. Beutler

bruce beutler,beutler
NAMEBruce Alan Beutler
BORNDecember 29, 1957 (Chicago, IL, USA)
AGE53 years
NATIONALITYAmerican
PARENTSEmest Beutler (geneticist) and Brondelle May Fleisher (journalist)
BETTER HALFBarbara Beutler (divorced)
CHILDRENDaniel, Eliot and Jonathan
ACADEMIC BACKGROUNDB.A., University of California, San Diego, 1976
M.D., Medicine, the University of Chicago, 1981
EXPERTISEImmunology
IMPORTANT SCIENTIFIC
ACCOMPLISHMENTS
the isolation of mouse tumor necrosis factor (TNF) and discovery of its inflammatory properties.
the invention of recombinant inhibitors for TNF, now widely used for the treatment of inflammatory diseases.
the discovery of the receptor for lipopolysaccharide (LPS), which revealed how mammals sense infection and how certain inflammatory diseases begin.
AWARDS & HONORS(1994) Outstanding Investigator Award (American Federation for Clinical Research,USA)
(2004) Robert Koch Prize (Robert Koch Stiftung, Germany)
(2006) William B. Coley Award (Cancer Research Institute, USA)
(2006) Gran Prix Charles-Leopold-Mayer (Académie des Sciences, France)
(2007) Balzan Prize (International Balzan Foundation, Italy and Switzerland)
(2007) Doctor of Medicine honoris causa from the Technical University of Munich
(2007) Frederik B. Bang Award (International Endotoxin and Innate Immunity Society)
(2008) National Academy of Sciences
(2009) Albany Medical Center Prize
(2011) Shaw Prize
the Nobel Prize in Physiology or Medicine 2011
AFFILIATIONthe Scripps Research Institute, La Jolla, CA, USA
University of Texas Southwestern Medical Center at Dallas, TX, USA
PRIZE MOTIVATION"for their discoveries concerning the activation of innate immunity"

Jules A. Hoffmann

jules hoffmann,hoffmann
NAMEJules A. Hoffmann
BORNAugust 2, 1941 (Echternach, Luxembourg)
AGE70 years
NATIONALITYFrench
ACADEMIC BACKGROUNDundergraduate degrees in Biology and Chemistry at the University of Strasbourg, France.
Ph.D. in Biology at the University of Strasbourg in 1969
post-doctoral training at the Institute for Physiologische Chemie at Philipps Universitat in Marburg an der Lahn, Germany in 1973-1974.
EXPERTISEBiology
AWARDS & HONORS(2003) Cancer Research Institute William B. Coley Award
(2004) Robert Koch Prize
(2007) Balzan Prize together with Bruce A. Beutler for Innate Immunity
(2010) Lewis S. Rosenstiel Award (shared with Ruslan M. Medzhitov)
(2010) Keio Medical Science Prize
(2011) Gairdner Foundation International Award (shared with Shizuo Akira
(2011) Shaw Prize (shared with Bruce A. Beutler and Ruslan M. Medzhitov
(2011) CNRS Gold Medal
the Nobel Prize in Physiology or Medicine 2011
AFFILIATIONCNRS
PRIZE MOTIVATION"for their discoveries concerning the activation of innate immunity"

Ralph M. Steinman

ralph steinman,steinman
NAMERalph Marvin Steinman
BORNJanuary 14, 1943 (Montreal, Quebec, Canada)
DIEDSeptember 30, 2011
AGE68 years
NATIONALITYCanadian
ACADEMIC BACKGROUNDB.Sc. degree from McGill University in 1963
M.D.(magna cum laude) from Harvard Medical School in 1968
EXPERTISEImmunology and Cell Biology
AWARDS & HONORS(1998) William B. Coley Award
(1999) Robert Koch Prize
(2003) Gairdner Foundation International Award
(2007) Albert Lasker Award for Basic Medical Research
(2009) Albany Medical Center Prize (shared with Charles A. Dinarello and Bruce Beutler)
the Nobel Prize in Physiology or Medicine 2011
AFFILIATIONRockefeller University, New York, USA
PRIZE MOTIVATION"for his discovery of the dendritic cell and its role in adaptive immunity"

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